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CLASSIFICATION AND TREATMENT OF THE JUVENILE IDIOPATHIC INFLAMMATORY MYOPATHIES

Identifieur interne : 002897 ( Main/Exploration ); précédent : 002896; suivant : 002898

CLASSIFICATION AND TREATMENT OF THE JUVENILE IDIOPATHIC INFLAMMATORY MYOPATHIES

Auteurs : Lisa G. Rider ; Frederick W. Miller

Source :

RBID : ISTEX:AD956358179DF493274E11A623E069A2E3ED2BD1

English descriptors

Abstract

The idiopathic inflammatory myopathies (IIMs) of childhood are a rare group of disorders characterized by chronic skeletal muscle inflammation of unknown cause, with onset at less than 18 years of age. The first pediatric case of dermatomyositis was reported by Potain in 1875, 240 and the early history of adult and juvenile dermatomyositis was thoroughly reviewed by Steiner in 1903.295 Research in this century has concentrated on the epidemiology, etiology, pathogenesis, and clinical characteristics of juvenile dermatomyositis (JDM), the most common of the juvenile IIMs. This article highlights other aspects of the juvenile IIMs: first, the classification of juvenile myositis and the placement of JDM into a broader context of illnesses that share idiopathic chronic muscle inflammation and often meet the same clinical diagnostic criteria 26 and second, the clinical management of these disorders.

Url:
DOI: 10.1016/S0889-857X(05)70350-1


Affiliations:


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Le document en format XML

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<term>Acad</term>
<term>Acad dermatol</term>
<term>Acta</term>
<term>Acta neurol scand</term>
<term>Acute onset</term>
<term>Adult myositis</term>
<term>Adult patients</term>
<term>Arch dermatol</term>
<term>Arthritis</term>
<term>Arthritis rheum</term>
<term>Autoantibody</term>
<term>Azathioprine</term>
<term>Biologics evaluation</term>
<term>Biopsy</term>
<term>Calcification</term>
<term>Calcinosis</term>
<term>Calcinosis cutis</term>
<term>Calcinosis universalis</term>
<term>Case report</term>
<term>Certain subsets</term>
<term>Childhood dermatomyositis</term>
<term>Childhood polymyositis</term>
<term>Clin</term>
<term>Clinical characteristics</term>
<term>Clinicopathologic</term>
<term>Concurrent prednisone</term>
<term>Connective tissue disease</term>
<term>Connective tissue diseases</term>
<term>Corticosteroid</term>
<term>Corticosteroid therapy</term>
<term>Creatine kinase</term>
<term>Curr opin rheumatol</term>
<term>Cutaneous</term>
<term>Cutaneous disease</term>
<term>Cutaneous lesions</term>
<term>Cutaneous manifestations</term>
<term>Cyclophosphamide</term>
<term>Cyclosporine</term>
<term>Cytotoxic</term>
<term>Cytotoxic agents</term>
<term>Dermatol</term>
<term>Dermatomyositis</term>
<term>Dermatornyositis</term>
<term>Disease activity</term>
<term>Disease courses</term>
<term>Disease severity</term>
<term>Dysphagia</term>
<term>Dystrophic calcification</term>
<term>Engl</term>
<term>Focal myositis</term>
<term>Functional disability</term>
<term>Functional outcome</term>
<term>Gastrointestinal ulceration</term>
<term>High frequency</term>
<term>Idiopathic</term>
<term>Iims</term>
<term>Illness onset</term>
<term>Immunoglobulin</term>
<term>Inclusion body myositis</term>
<term>Infantile myositis</term>
<term>Infantile polymyositis</term>
<term>Inflammation</term>
<term>Inflammatory</term>
<term>Inflammatory myopathies</term>
<term>Inflammatory myopathy</term>
<term>Interstitial</term>
<term>Interstitial lung disease</term>
<term>Intravenous</term>
<term>Intravenous gammaglobulin</term>
<term>Intravenous immunoglobulin</term>
<term>Intravenous immunoglobulin therapy</term>
<term>Ivig</term>
<term>Juvenile cases</term>
<term>Juvenile dermatomyositis</term>
<term>Juvenile dermatornyositis</term>
<term>Juvenile idiopathic</term>
<term>Juvenile iims</term>
<term>Juvenile myositis</term>
<term>Kawasaki disease</term>
<term>Lancet</term>
<term>Lupus</term>
<term>Lyme disease</term>
<term>Methotrexate</term>
<term>Methotrexate therapy</term>
<term>Methylprednisolone</term>
<term>Mglkgld</term>
<term>Msas</term>
<term>Muscle biopsies</term>
<term>Muscle biopsy</term>
<term>Muscle enzymes</term>
<term>Muscle strength</term>
<term>Myopathy</term>
<term>Myositis</term>
<term>Myositis onset</term>
<term>Myositis patients</term>
<term>Neurol</term>
<term>Normal strength</term>
<term>Nuclear protein</term>
<term>Orbital myositis</term>
<term>Osteoporosis</term>
<term>Pachman</term>
<term>Pediatr</term>
<term>Pediatr neurol</term>
<term>Pediatric</term>
<term>Personal communication</term>
<term>Physical therapy</term>
<term>Polymyositis</term>
<term>Poor prognosis</term>
<term>Prednisone</term>
<term>Prednisone dose</term>
<term>Prognosis</term>
<term>Prognostic</term>
<term>Pulse cyclophosphamide</term>
<term>Pulse methylprednisolone</term>
<term>Rash</term>
<term>Recalcitrant disease</term>
<term>Refractory</term>
<term>Regimen</term>
<term>Remission</term>
<term>Residual disability</term>
<term>Retrospective</term>
<term>Rheum</term>
<term>Rheumatoid arthritis</term>
<term>Rheumatol</term>
<term>Rider miller</term>
<term>Risk factors</term>
<term>Scleroderma</term>
<term>Serum muscle enzymes</term>
<term>Severe dysphagia</term>
<term>Severe polymyositis</term>
<term>Side effects</term>
<term>Skin disease</term>
<term>Skin rashes</term>
<term>Small number</term>
<term>Steroid</term>
<term>Subset</term>
<term>Successful treatment</term>
<term>Surg</term>
<term>Syndrome</term>
<term>Targoff</term>
<term>Therapy</term>
<term>Toxicity</term>
<term>Ulceration</term>
<term>Unpublished observation</term>
<term>Unpublished observations</term>
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<div type="abstract">The idiopathic inflammatory myopathies (IIMs) of childhood are a rare group of disorders characterized by chronic skeletal muscle inflammation of unknown cause, with onset at less than 18 years of age. The first pediatric case of dermatomyositis was reported by Potain in 1875, 240 and the early history of adult and juvenile dermatomyositis was thoroughly reviewed by Steiner in 1903.295 Research in this century has concentrated on the epidemiology, etiology, pathogenesis, and clinical characteristics of juvenile dermatomyositis (JDM), the most common of the juvenile IIMs. This article highlights other aspects of the juvenile IIMs: first, the classification of juvenile myositis and the placement of JDM into a broader context of illnesses that share idiopathic chronic muscle inflammation and often meet the same clinical diagnostic criteria 26 and second, the clinical management of these disorders.</div>
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